Intraneuron for clinical practices

A neurologist in his fifties talking with an older patient in a bright consulting room

Most people arrive here looking for the Memory Exam, the at-home screening test we sell directly to the public. That is one of the two things we do.

The other is building and operating the software that community neurology practices use to deliver dementia care at scale. If you are a practice, a health system or a research site, this page is for you.

The CMS GUIDE model

GUIDE, Guiding an Improved Dementia Experience, is a Centers for Medicare and Medicaid Services model for delivering coordinated dementia care. Participating practices take on structured responsibilities around assessment, care planning, caregiver support and ongoing follow-up.

Meeting those responsibilities consistently, for every patient, is an operational problem before it is a clinical one. Intraneuron implements and operates the software workflow that makes it repeatable.

A Latina woman in her fifties and her father in his seventies listening to a pharmacist pointing something out on a box

What the platform handles

  • Registration and intake. Patients complete registration and intake forms before they arrive, so the visit starts with the paperwork already done.
  • Medical and neuropsychological scales. The instruments a practice already relies on, administered and scored consistently rather than re-keyed from paper.
  • Audio questionnaires. Scales administered by voice, which is how we measure verbal memory and fluency and what makes remote administration practical for older patients.
  • Caregiver-reported measures. Collected as part of the same process rather than chased separately.
  • Structured follow-up. Workflow that tracks where each patient is, so scheduled reassessment happens instead of depending on someone remembering.
  • Embedded clinical trial recruitment. Identifying candidates for research out of routine care, rather than running recruitment as a separate effort.

These are components rather than a fixed product. Practices differ, and so do the pathways they need, so we build the workflow a practice runs rather than asking it to adopt ours.

This is the work described in Implementing the CMS GUIDE Dementia Care Model in a Community Neurology Practice with Digital Tools, Standardized Scales and Embedded Clinical Trial Recruitment, published in Neurology in 2026.

A Black woman in her seventies waiting in a bright airy reception, coat on lap

Memory clinic workflow

we also provide the workflow infrastructure behind memory clinics: intake, structured assessment, scoring, reporting and scheduled follow-up, organised so a clinic runs the same pathway for every patient instead of assembling one per visit.

It is the same platform underneath. A practice running a memory clinic and a practice participating in GUIDE are doing much the same operational work, and both are better served by software built for the pathway than by a general-purpose record system.

A white man in his seventies with a printed report and a pen on a kitchen table
Two old friends in their seventies hanging washing out in the afternoon sun

Evidence

Our voice-recognition cognitive screening has been evaluated against standard neuropsychological assessment and published in peer-reviewed journals.

  • Convergent Validity between Standard Neuropsychological Assessment and Web-Based Voice-Recognition Neuropsychological Assessment. Archives of Clinical Neuropsychology, September 2024.
  • Convergent Validity and Classification Agreement Between Traditional Cognitive Screening Instruments and a Novel, Electronic-based, Voice-recognition Cognitive Screening Tool. Neurology, April 2024.
  • Hal, do I have memory problems? A pilot study investigating a voice recognition cognitive screening tool. Alzheimer's & Dementia, December 2021.

The underlying technology is covered by United States patents 11,547,345 and 12,226,221.

Who builds it

Intraneuron was founded in 2013 by Gregory Sahagian, M.D., a neurologist and chief executive of The Neurology Center of Southern California, and Vidar Vignisson, a technology executive with more than thirty years building software.

The platform is developed alongside practising clinicians rather than at a distance from them, including two board-certified clinical neuropsychologists. You can read more about the team.

An Asian man in his late sixties at a library table with afternoon light across it

Talk to us

if you are evaluating Intraneuron for a practice, a health system or a research site, email info@intraneuron.com and tell us what you are trying to solve.

We are based in San Diego, California.

A white woman in her fifties turning down a radio to hear the other person better
A white man in his seventies tending plants on a sunny balcon

Where to go next

if you are evaluating Intraneuron for a practice or a health system, we would rather have a conversation than send a brochure.

You can also read about the team, the company, or the normative study we are running.

Get in touch